Delayed post‐dialysis recovery times are associated with relative changes in intracellular and extracellular fluid ratios between different body compartments

Author:

Yoowannakul Suree1,Vongsanim Surachet2,Tangvoraphonkchai Kamonwan3,Davenport Andrew4ORCID

Affiliation:

1. Division of Nephrology, Department of Medicine Bhumibol Adulyadej Hospital Bangkok Thailand

2. Renal Division, Department of Internal Medicine Chiang Mai University Chiang Mai Thailand

3. Faculty of Medicine Mahasarakham University Maha Sarakham Thailand

4. UCL Department of Renal Medicine, Royal Free Hospital University College London London UK

Abstract

AbstractIntroductionHemodialysis patient groups have advocated reducing dialysis fatigue and symptoms. We investigated whether compartmental fluid shifts were associated with peri‐dialytic fatigue and symptoms.MethodsSessional dialysis records of patients reporting both a short and delayed recovery (<1 h and ≥1 h) with corresponding bioimpedance measurements were reviewed.ResultsOne hundred and twenty‐four patients reported both short and delayed recovery times, mean age 66.0 ± 14.8 years, 66.1% male. Differences between sessions included higher distress thermometer [4 (1–6) vs. 3 (0–5)], fatigue [4 (0–9) vs. 2 (0–7)], total symptom scores [20.5 (12.3–34.5) vs. 16 (7–28)], change in extracellular water to total body water ratios between body compartments [right leg/left arm 2.36 (1.23–4.19) vs. 1.28 (0.12–2.01), all p < 0.01] with delayed recovery, and more hemodialysis than hemodiafiltration sessions (χ2 4.6, p = 0.02).ConclusionSessions with prolonged recovery times were associated with more peri‐dialytic symptoms, psychological distress, and hemodialysis mode, and greater changes in compartmental fluid shifts.

Publisher

Wiley

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