Successful treatment with granulocyte and monocyte adsorption apheresis for plaque‐type skin lesions in patients with psoriatic arthritis

Author:

Seishima Mariko1,Hachiken Hideki1,Furukawa Takuma1,Yamamoto Junichiro2

Affiliation:

1. Department of Dermatology Asahi University Hospital Gifu Japan

2. Department of Nephrology Asahi University Hospital Gifu Japan

Abstract

AbstractIntroductionGranulocyte and monocyte adsorption apheresis (GMA) is usually performed weekly for refractory skin diseases, such as generalized pustular psoriasis and psoriatic arthritis (PsA).MethodsFour patients with PsA who were refractory to previous treatments were enrolled. They received five or ten sessions of GMA. We assessed the clinical conditions of each patient and laboratory findings before and after GMA.ResultsGMA was effective in plaque‐type skin eruptions in all four patients with PsA. It was also effective in joint symptoms in three patients with PsA with mild symptoms, but was ineffective in one patient with severe joint symptoms.ConclusionGMA may be recommended to PsA patients with skin eruptions and mild joint symptoms.

Publisher

Wiley

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