Affiliation:
1. Department of Endocrinology, Metabolism and Nephrology Keio University School of Medicine Tokyo Japan
2. Department of Nephrology International University of Health and Welfare Narita Hospital Chiba Japan
3. Apheresis and Dialysis Center Keio University School of Medicine Tokyo Japan
Abstract
AbstractIntroductionWe aimed to determine the correlation between the serum urea‐to‐creatinine ratio and residual kidney function (RKF) in patients undergoing peritoneal dialysis (PD), as well as its predictive value for PD‐related outcomes.MethodsThis study included a cross‐sectional study to assess the correlation between serum urea‐to‐creatinine ratio and RKF in 50 patients on PD and a retrospective cohort study to assess the association between serum urea‐to‐creatinine ratio and PD‐related outcomes in 122 patients who initiated PD.ResultsSerum urea‐to‐creatinine ratios had significant positive correlations with renal Kt/V and creatinine clearance values (r = 0.60, p < 0.001 and r = 0.61, p < 0.001, respectively). Additionally, serum urea‐to‐creatinine ratio was significantly associated with a lower risk of transfer to hemodialysis or PD/hemodialysis hybrid therapy (hazard ratio: 0.84, 95% confidence interval: 0.75–0.95).ConclusionThe serum urea‐to‐creatinine ratio can be an indicator of RKF and a prognostic factor in patients undergoing PD.