A field study evaluating the activity of N8‐GP in spiked plasma samples at clinical haemostasis laboratories
Author:
Affiliation:
1. Laboratory Corporation of America Holdings Colorado Coagulation Englewood Colorado USA
2. Novo Nordisk A/S Søborg Denmark
3. Novo Nordisk A/S Måløv Denmark
Funder
Novo Nordisk
Publisher
Wiley
Subject
Genetics (clinical),Hematology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/hae.13813
Reference24 articles.
1. Enhancing the pharmacokinetic properties of recombinant factor VIII: first-in-human trial of glycoPEGylated recombinant factor VIII in patients with hemophilia A
2. Safety and efficacy of a glycoPEGylated rFVIII (turoctocog alpha pegol, N8-GP) in paediatric patients with severe haemophilia A
3. A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models
4. Clinical evaluation of glycoPEGylated recombinant FVIII: Efficacy and safety in severe haemophilia A
5. Current laboratory practices in the diagnosis and management of haemophilia: a global assessment
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2. A global comparative field study to evaluate the factor VIII activity of efanesoctocog alfa by one‐stage clotting and chromogenic substrate assays at clinical haemostasis laboratories;Haemophilia;2023-10-30
3. Plasma Clearance of Coagulation Factor VIII and Extension of Its Half-Life for the Therapy of Hemophilia A: A Critical Review of the Current State of Research and Practice;International Journal of Molecular Sciences;2023-05-11
4. Measurement of extended half-life recombinant FVIII molecules: In vitro and ex vivo evidence of relevant assay discrepancies;Research and Practice in Thrombosis and Haemostasis;2023-02
5. A Review of Factor VIII and Factor IX Assay Methods for Monitoring Extended Half-Life Products in Hemophilia A and B;Methods in Molecular Biology;2023
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