Can the diagnostic reliability of the thrombin generation test as a global haemostasis assay be improved? The impact of calcium chloride concentration

Author:

Parunov L. A.12ORCID,Surov S. S.12,Liang Y.1,Lee T. K.1,Ovanesov M. V.1ORCID

Affiliation:

1. Office of Tissues and Advanced Therapies; CBER; US Food and Drug Administration; Silver Spring MD USA

2. Center for Theoretical Problems of Physicochemical Pharmacology; Moscow Russia

Publisher

Wiley

Subject

Genetics(clinical),Hematology,General Medicine

Reference44 articles.

1. Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B;Dargaud;Thromb Haemost,2005

2. The role of factor XI in thrombin generation induced by low concentrations of tissue factor;Keularts;Thromb Haemost,2001

3. Importance of factor-IX-dependent prothrombinase formation - the Josso pathway - in clotting plasma;Xi;Haemostasis,1989

4. Factor XII-independent activation of factor XI in plasma: effects of sulfatides on tissue factor-induced coagulation;Gailani;Blood,1993

5. Thrombin generation and phenotypic correlation in haemophilia A;Beltran-Miranda;Haemophilia,2005

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