Research and policy implications of a recently published controlled study in previously untreated haemophilia patients at high risk of inhibitor development
Author:
Affiliation:
1. Health Research Methods; Evidence and Impact; McMaster University; Hamilton ON Canada
Funder
Bayer
Baxalta
Biogen Idec
Grifols
Novo Nordisk
Pfizer
Octapharma
Publisher
Wiley
Subject
Genetics(clinical),Hematology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/hae.13176/fullpdf
Reference22 articles.
1. Are randomized clinical trials the only truth? Not always;Aledort;J Thromb Haemost,2006
2. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia;Manco-Johnson;N Engl J Med,2007
3. A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study);Gringeri;J Thromb Haemost,2011
4. Randomized, controlled, parallel-group trial of routine prophylaxis vs. on-demand treatment with sucrose-formulated recombinant factor VIII in adults with severe hemophilia A (SPINART);Manco-Johnson;J Thromb Haemost,2013
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2. Incidence of inhibitor development in PUPs with severe Haemophilia A in the CEE region between 2005 and 2015;Thrombosis Research;2021-02
3. Hemophilia A with inhibitor: Immune tolerance induction (ITI) in the mirror of time;Transfusion and Apheresis Science;2019-10
4. Lower inhibitor risk of plasma-derived factor VIII concentrates versus recombinant factor VIII concentrates in patients with severe haemophilia A : result from SIPPET study and comments;HEMATOLOGIE;2019
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