UpFrontPSMA: a randomized phase 2 study of sequential 177 Lu‐PSMA‐617 and docetaxel vs docetaxel in metastatic hormone‐naïve prostate cancer (clinical trial protocol)

Author:

Dhiantravan Nattakorn123ORCID,Emmett Louise456,Joshua Anthony M.567,Pattison David A.89,Francis Roslyn J.101112,Williams Scott23613,Sandhu Shahneen23614,Davis Ian D.61516,Vela Ian1718,Neha Nitika19,Bressel Mathias19,Murphy Declan G.2320ORCID,Hofman Michael S.1236ORCID,Azad Arun A.23614ORCID

Affiliation:

1. Molecular Imaging and Therapeutic Nuclear Medicine Peter MacCallum Cancer Centre Melbourne VICAustralia

2. Prostate Cancer Theranostics and Imaging Centre of Excellence (ProsTIC) Peter MacCallum Cancer Centre Melbourne VICAustralia

3. Sir Peter MacCallum Department of Oncology University of Melbourne Melbourne VIC Australia

4. Department of Theranostics St Vincent's Hospital Sydney NSWAustralia

5. Garvan Institute of Medical Research Sydney NSWAustralia

6. Australian and New Zealand Urogenital and Prostate (ANZUP) Cancer Trials Group Sydney NSWAustralia

7. Department of Medical Oncology The Kinghorn Cancer Centre St Vincent’s Hospital Sydney NSWAustralia

8. Department of Nuclear Medicine & Specialised PET Services Royal Brisbane & Women's Hospital Brisbane QLDAustralia

9. School of Medicine University of Queensland Brisbane QLDAustralia

10. Department of Nuclear Medicine Sir Charles Gairdner Hospital Perth WAAustralia

11. Medical School University of Western Australia Perth WAAustralia

12. The Australasian Radiopharmaceutical Trial network (ARTnet) Sydney NSWAustralia

13. Division of Radiation Oncology Peter MacCallum Cancer Centre Melbourne VIC Australia

14. Department of Medical Oncology Peter MacCallum Cancer Centre Melbourne VICAustralia

15. Eastern Health Melbourne VICAustralia

16. Eastern Health Clinical School Monash University Melbourne VICAustralia

17. Department of Urology Princess Alexandra Hospital Woolloongabba QLDAustralia

18. Prostate Cancer Research Centre‐Queensland Translational Research Institute Queensland University of Technology Brisbane QLDAustralia

19. Centre for Biostatistics and Clinical Trials (BaCT) Peter MacCallum Cancer Centre Melbourne VIC Australia

20. Division of Cancer Surgery Peter MacCallum Cancer Centre Melbourne VIC Australia

Funder

U.S. Department of Defense

Movember Foundation

Publisher

Wiley

Subject

Urology

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