Ultraviolet Radiation‐Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma

Author:

Ahmad Israr1,Muneer Kashiff M.1,Chang Michelle E.1,Nasr Hana M.1,Clay Jacqueline M.1,Huang Conway C.1,Yusuf Nabiha123

Affiliation:

1. Department of Dermatology Skin Diseases Research Center Birmingham AL

2. Veteran Affairs Medical Center Birmingham AL

3. Comprehensive Cancer Center University of Alabama Birmingham AL

Funder

U.S. Department of Defense

Publisher

Wiley

Subject

Physical and Theoretical Chemistry,General Medicine,Biochemistry

Reference53 articles.

1. Skin Cancer Foundation(2010) Available at:http://www.skincancer.org/skin-cancer-information/basal‐cell‐carcinoma.

2. National Cancer Institute National Institute of Health(2014)http://www.cancer.gov/cancertopics/pdq/treatment/skin/HealthProfessional/page4.

3. Sunburn and p53 in the onset of skin cancer

4. Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion;Brash D. E.;J. Investig. Dermatol. Symp. Proc.,1996

5. The role of UV radiation in the development of basal cell carcinoma;Situm M.;Coll. Antropol.,2008

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