Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome-Reference-Cited by-同舟云学术

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

Published:2019-09-10 Issue:10 Volume:110 Page:3358-3367
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:Cancer Sci

Author:

Kubota Yasuo¹^ORCID,Uryu Kumiko¹,Ito Tatsuya²,Seki Masafumi¹,Kawai Tomoko³,Isobe Tomoya¹,Kumagai Tadayuki⁴,Toki Tsutomu²,Yoshida Kenichi⁵,Suzuki Hiromichi⁵,Kataoka Keisuke⁵^ORCID,Shiraishi Yuichi⁶,Chiba Kenichi⁶,Tanaka Hiroko⁷,Ohki Kentaro⁸,Kiyokawa Nobutaka⁸,Kagawa Jiro⁴,Miyano Satoru⁷,Oka Akira¹,Hayashi Yasuhide⁹,Ogawa Seishi⁵,Terui Kiminori²,Sato Atsushi¹⁰,Hata Kenichiro³,Ito Etsuro²,Takita Junko¹^ORCID

Affiliation:

1. Department of Pediatrics Graduate School of Medicine, The University of Tokyo Tokyo Japan

2. Department of Pediatrics Hirosaki University Graduate School of Medicine Hirosaki Japan

3. Department of Maternal‐Fetal Biology National Research Institute for Child Health and Development Tokyo Japan

4. Department of Pediatrics Fujieda Municipal General Hospital Fujieda Japan

5. Department of Pathology and Tumor Biology Graduate School of Medicine, Kyoto University Kyoto Japan

6. Section of Genome Analysis Platform Center for Cancer Genomic and Advanced Therapeutics National Cancer Center Tokyo Japan

7. Laboratory of DNA Information Analysis, Human Genome Center Institute of Medical Science University of Tokyo Tokyo Japan

8. Department of Pediatric Hematology and Oncology Research National Research Institute for Child Health and Development Setagaya‐ku Japan

9. Institute of Physiology and Medicine Jobu University Takasaki Japan

10. Department of Hematology and Oncology Miyagi Children's Hospital Sendai Japan

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.14160

Reference30 articles.

1. Risks of leukaemia and solid tumours in individuals with Down's syndrome

2. Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations

3. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation

4. DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

5. Integrated molecular analysis of clear-cell renal cell carcinoma

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