Open-label randomized non-inferiority trial of a fixed-dose combination of glimepiride and atorvastatin for the treatment of people whose Type 2 diabetes is uncontrolled on metformin

Author:

Ambery P.1,Stylianou A.2,Atkinson G.3,Dott C.3,Baylor Curtis L.3,Haque N.3,LaCroix K.4,Min K. W.5,

Affiliation:

1. Department of Medicine; Addenbrooke's Hospital; Cambridge UK

2. Clinical Statistics; GlaxoSmithKline; Stevenage UK

3. Alternative Discovery and Development; GlaxoSmithKline; Brentford UK

4. Global Clinical Safety and Pharmacovigilance; GlaxoSmithKline; Research Triangle Park NC USA

5. Diabetes Centre; Eulji Hospital; Eulji University School of Medicine; Seoul Republic of Korea

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference26 articles.

1. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD);Inzucchi;Diabetologia,2012

2. Intensive glucose lowering and cardiovascular disease prevention in diabetes: reconciling the recent clinical trial data;Mazzone;Circulation,2010

3. Dyslipidemia in type 2 diabetes mellitus;Mooradian;Nat Clin Pract Endocrinol Metab,2009

4. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines;Stone;Circulation,2014

5. National Institute for Health and Care Excellence Lipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease [Guideline CG181] 2014 https://www.nice.org.uk/guidance/cg181/resources/guidance-lipid-modification-cardiovascular-risk-assessment-and-the-modification-of-blood-lipids-for-the-primary-and-secondary-prevention-of-cardiovascular-disease-pdf

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