Population pharmacokinetic/pharmacodynamic modelling of eltrombopag in healthy volunteers and subjects with chronic liver disease
Author:
Affiliation:
1. ICON Development Solutions; Marlow Buckinghamshire UK
2. Clinical Pharmacology Modeling & Simulation; GlaxoSmithKline; Research Triangle Park NC USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12244/fullpdf
Reference19 articles.
1. Thrombocytopenia as a surrogate for cirrhosis and a marker for the identification of patients at high risk for hepatocellular carcinoma;Lu;Cancer,2006
2. Survival and prognostic factors in 366 patients with compensated cirrhosis type B: a multicenter study;Realdi;J Hepatol,1994
3. The role of thrombopoietin in the thrombocytopenia patients with liver cirrhosis;Rios;Am J Gastroenterol,2005
4. Partial splenic embolization in patients with cirrhosis: efficacy, tolerance and long term outcome in 32 patients;N'Kontchou;Eur J Gastroenterol Hepatol,2005
5. An association of soluble CD40 ligand (CD154) with adverse reactions to platelet transfusions;Blumberg;Transfusion,2006
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