Using an animal model to predict the effective human dose for oral multiple sclerosis drugs-Reference-Cited by-同舟云学术

Using an animal model to predict the effective human dose for oral multiple sclerosis drugs

Published:2022-11-23 Issue:3 Volume:16 Page:467-477
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clinical Translational Sci

Author:

Liu Wei¹²,Yu Zhiheng¹²,Wang Ziyu¹³,Waubant Emmanuelle L.⁴,Zhai Suodi¹,Benet Leslie Z.¹²^ORCID

Affiliation:

1. Department of Pharmacy Peking University Third Hospital Beijing China

2. Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine University of California San Francisco San Francisco California USA

3. School of Basic Medical Sciences and Clinical Pharmacy China Pharmaceutical University Nanjing China

4. Weill Institute for Neurosciences and San Francisco Multiple Sclerosis Center University of California San Francisco San Francisco California USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.13458

Reference46 articles.

1. Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis

2. Fingolimod (GILENYA) Drug Label Washington (USA).https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022527s000lbl.pdf. Accessed March 28 2022.

3. Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

4. Guidance for Industry: Estimating the maximum safe starting dose in initial clinical trials for therapeutics in adult healthy volunteers 2005 Rockville MD.https://www.fda.gov/media/72309/download. Accessed March 28 2022.

5. Ofatumumab Pharmacology Review(s) Washington (USA).https://www.accessdata.fda.gov/drugsatfda_docs/nda/2009/125326s000_PharmR.pdf. Accessed March 28 2022.

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