Promising anticonvulsant and/or analgesic compounds among 5‐chloro‐2‐ or 5‐chloro‐4‐methyl derivatives of xanthone coupled to aminoalkanol moieties—Design, synthesis and pharmacological evaluation-Reference-Cited by-同舟云学术

Promising anticonvulsant and/or analgesic compounds among 5‐chloro‐2‐ or 5‐chloro‐4‐methyl derivatives of xanthone coupled to aminoalkanol moieties—Design, synthesis and pharmacological evaluation

Published:2022-12-16 Issue:2 Volume:101 Page:278-325
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Mazur Gabriela¹,Pańczyk‐Straszak Katarzyna¹,Rapacz Anna²,Kiszela Jan³,Smolik Magdalena⁴,Gawlik Maciej⁴,Walczak Maria⁴,Czekajewska Joanna⁵,Poloczek Celina³,Karczewska Elżbieta⁵,Żesławska Ewa⁶,Nitek Wojciech⁷,Niedbał Anna³,Leśniak Joanna³,Ciapala Katarzyna⁸,Pawlik Katarzyna⁸,Mika Joanna⁸,Waszkielewicz Anna M.¹

Affiliation:

1. Department of Bioorganic Chemistry, Chair of Organic Chemistry, Faculty of Pharmacy Jagiellonian University Medical College Kraków Poland

2. Department of Pharmacodynamics, Faculty of Pharmacy Jagiellonian University Medical College Kraków Poland

3. Faculty of Pharmacy Jagiellonian University Medical College Kraków Poland

4. Chair and Department of Toxicology, Faculty of Pharmacy Jagiellonian University Medical College Kraków Poland

5. Department of Microbiology, Faculty of Pharmacy Jagiellonian University Medical College Kraków Poland

6. Institute of Biology Pedagogical University of Krakow Kraków Poland

7. Department of Crystallochemistry and Crystallophysics, Faculty of Chemistry Jagiellonian University Kraków Poland

8. Department of Pain Pharmacology Maj Institute of Pharmacology Kraków Poland

Funder

Uniwersytet Jagielloński Collegium Medicum

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.14102

Reference58 articles.

1. Anti-Cancer Effects of Xanthones from Pericarps of Mangosteen

2. Crystal structure determination and refinementviaSIR2014

3. Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

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