Maximum Effect of Triptans in Migraine? A Comment-Reference-Cited by-同舟云学术

Maximum Effect of Triptans in Migraine? A Comment

Published:2008-07 Issue:7 Volume:28 Page:767-768
ISSN:0333-1024
Container-title:Cephalalgia
language:en
Short-container-title:Cephalalgia

Author:

Tfelt-Hansen P¹

Affiliation:

1. Danish Headache Centre, Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark

Abstract

The efficacy of triptans in the treatment of migraine was recently contested. How high is then the maximum effect of a triptan? After subcutaneous naratriptan 10 mg a 88% pain-free response was observed. This result was obtained despite the fact that more half of the patients had a migraine duration of > 4 h. These results indicate that subcutaneous naratriptan in a high dose can overcome central sensitization that occurs in migraine attacks.

Publisher

SAGE Publications

Subject

Clinical Neurology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1111/j.1468-2982.2007.01415.x

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4. Guidelines for Controlled Trials of Drugs in Migraine: Second Edition

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