Fitness landscapes emerging from pharmacodynamic functions in the evolution of multidrug resistance
Author:
Affiliation:
1. School of Biological Sciences; The University of Queensland; Brisbane Qld Australia
Publisher
Wiley
Subject
Ecology, Evolution, Behavior and Systematics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jeb.12355/fullpdf
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2. Andersson , D.I. Patin , S.M. Nilsson , A.I. Kugelberg , E. 2007 The biological cost of antibiotic resistance Enzyme-Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and Prospects for Inhibition R.A. Bonomo M.E. Tolmaski 339 348 ASM Press Washington, DC, USA
3. Two-drug antimicrobial chemotherapy: a mathematical model and experiments with mycobacterium marinum;Ankomah;PLoS Pathog.,2012
4. The pharmaco -, population and evolutionary dynamics of multi-drug therapy: experiments with S. aureus and E. coli and computer simulations;Ankomah;PLoS Pathog.,2013
5. Recombination dynamics and the fitness landscape;Bergman;Physica D,1992
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