Inherited thrombophilia in women with poor aPL-related obstetric history: prevalence and outcomes. Survey of 208 cases from the European Registry on Obstetric Antiphospholipid Syndrome cohort

Author:

Alijotas-Reig Jaume12,Ferrer-Oliveras Raquel3,Esteve-Valverde Enrique14,Ruffatti Amelia5,Tincani Angela6,Lefkou Elmina7,Bertero Maria Tiziana8,Espinosa Gerard9,Coloma Emmanuel9,de Carolis Sara10,Rovere-Querini Patrizia11,Canti Valentina1112,Picardo Elisa13,Fredi Micaela6,Mekinian Arsene14,

Affiliation:

1. Systemic Autoimmune Disease Unit; Department of Internal Medicine; Vall d'Hebron University Hospital; Barcelona Spain

2. Department of Medicine; Universitat Autonoma; Barcelona Spain

3. Obstetric and Gynaecolgy Department; Vall d'Hebron University Hospital; Universitat Autonoma; Barcelona Spain

4. Internal Medicine Department; Althaia Healthcare Network of Manresa; Barcelona Spain

5. Rheumatology Unit; Department of Clinical and Experimental Medicine Azienda Ospedaliera; University of Padua; Padua Italy

6. Rheumatology and Clinial Immunology Unit; Ospedale Civile; Brescia Italy

7. Haematology Unit; Hippokration Hospital of Thessaloniki; Thessaloniki Greece

8. Department of Clinical Immunology; A.O. Mauriziano-Umberto I; Turin Italy

9. Systemic Autoimmune Diseases Service; Hospital Clinic; Universitat de Barcelona; Barcelona Spain

10. Depatment of Gynaecology; Gemmeli Hospital; Catholic University; Roma Italy

11. Pregnancy and Rheumatic Diseases Clinic Unit of Medicine and Clinical Immunology IRCCS Ospedale San Raffaele Università Vita-Salute San Raffaele; Milano Italy

12. Laboratorio Autoimmunità e Inflammazione Voscolare - San Raffaele DIBIT; Milano Italy

13. Department of Obstetrics and Gynaecology; University of Turin; Turin Italy

14. Department of Medicine; Hôpital Saint-Antoine; Universite Est Parisien; Paris France

Funder

EUROAPS project

Publisher

Wiley

Subject

Obstetrics and Gynecology,Reproductive Medicine,Immunology,Immunology and Allergy

Reference34 articles.

1. Antiphospholipid syndrome. ACOG Practice Bulletin;Obstet Gynecol,2012

2. The European Registry on Obstetric Antiphospholipid Syndrome (EUROAPS): a preliminary first year report;Alijotas-Reig;Lupus,2012

3. Histopathological findings in placentae from patients with intra-uterine fetal death and antiphospholipid antibodies;Out;Eur J Obstet Gynaecol Reprod Biol,1991

4. Heparin prevents antiphospholipid-induced fetal loss by inhibiting complement activation;Girardi;Nat Med,2004

5. Hipocomplementemia C3 y C4 en el síndrome antifosfolípido obstétrico;Carbone;Rev Clin Esp,2008

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