In silico and in vitro immunogenicity assessment of B-domain-modified recombinant factor VIII molecules
Author:
Affiliation:
1. Novo Nordisk A/S; Copenhagen Denmark
Funder
Novo Nordisk
Publisher
Wiley
Subject
Genetics (clinical),Hematology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/hae.13555/fullpdf
Reference40 articles.
1. Building better drugs: developing and regulating engineered therapeutic proteins;Kimchi-Sarfaty;Trends Pharmacol Sci,2013
2. Many factor VIII products available in the treatment of hemophilia A: an embarrassment of riches?;Lieuw;J Blood Med,2017
3. Purification and characterization of a new recombinant factor VIII (N8);Thim;Haemophilia,2010
4. Biochemical and functional characterization of a recombinant monomeric factor VIII-Fc fusion protein;Peters;J Thromb Haemost,2013
5. Structural and functional characteristics of the B-domain-deleted recombinant factor VIII protein, r-VIII SQ;Sandberg;Thromb Haemost,2001
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