A Prospective, Randomized, Masked, Placebo‐Controlled Multisite Clinical Study of Grapiprant, an EP 4 Prostaglandin Receptor Antagonist (PRA), in Dogs with Osteoarthritis-Reference-Cited by-同舟云学术

A Prospective, Randomized, Masked, Placebo‐Controlled Multisite Clinical Study of Grapiprant, an EP 4 Prostaglandin Receptor Antagonist (PRA), in Dogs with Osteoarthritis

Published:2016-04-13 Issue:3 Volume:30 Page:756-763
ISSN:0891-6640
Container-title:Journal of Veterinary Internal Medicine
language:en
Short-container-title:J Vet Intern Med

Author:

Rausch‐Derra L.¹,Huebner M.²,Wofford J.¹,Rhodes L.¹

Affiliation:

1. Aratana Therapeutics Leawood KS

2. ClinData Services Ft. Collins CO

Publisher

Wiley

Subject

General Veterinary

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jvim.13948

Reference16 articles.

1. CJ-023,423, a Novel, Potent and Selective Prostaglandin EP4 Receptor Antagonist with Antihyperalgesic Properties

2. Grapiprant: an EP 4 prostaglandin receptor antagonist and novel therapy for pain and inflammation

3. Effects of the selective EP4 antagonist, CJ-023,423 on chronic inflammation and bone destruction in rat adjuvant-induced arthritis

4. Evaluation of the safety of long-term, daily oral administration of grapiprant, a novel drug for treatment of osteoarthritic pain and inflammation, in healthy dogs

5. Caregiver placebo effect for dogs with lameness from osteoarthritis

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