Successful pregnancy and delivery following microdissection testicular sperm extraction and intracytoplasmic sperm injection for non‐obstructive azoospermia after microsurgical varicocelectomy: A case report and review of the literature

Author:

Kamo Hisae12,Komiya Akira134ORCID,Ota Kuniaki15,Hiraoka Kenichiro1,Honma Koichi6,Kawai Kiyotaka1

Affiliation:

1. Department of Reproductive Medicine Kameda IVF Clinic Makuhari Chiba Japan

2. Department of Gynecology and Obstetrics Sanmu Medical Center Chiba Japan

3. Department of Urology Kameda Medical Center Chiba Japan

4. Department of Urology Chiba University Graduate School of Medicine Chiba Japan

5. Fukushima Medical Center for Children and Women Fukushima Medical University Fukushima Japan

6. Department of Diagnostic Pathology Kameda Medical Center Chiba Japan

Abstract

AbstractAlthough surgical varicocele treatment is generally considered to result in improved reproductive outcomes, we encountered a rare case of postoperative azoospermia in an infertile male patient who underwent microsurgical varicocelectomy for a palpable left‐sided varicocele with concomitant cryptozoospermia. More than 1 year after varicocelectomy, the patient still had not recovered from azoospermia. Thereafter, he underwent microdissection testicular sperm extraction (micro‐TESE), allowing him and his partner to obtain one good quality blastocyst via intracytoplasmic sperm injection following oocyte retrievals. Finally, the couple had a successful pregnancy following a frozen embryo transfer, and a live male infant was subsequently delivered to them at 39 weeks and 5 days. In cases of severe testicular dysfunction, varicocelectomy may worsen the postoperative semen parameters until azoospermia. Therefore, it is important to consider preoperative sperm cryopreservation and to explore the possibility of subsequent TESE.

Publisher

Wiley

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