An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans-Reference-Cited by-同舟云学术

An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans

Published:2020-09-26 Issue:1 Volume:14 Page:231-238
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Kim Anhye¹,Dueker Stephen R.²³,Hwang Jun Gi⁴⁵,Yoon Jangsoo⁴,Lee Sang‐Won⁶,Lee Hye Suk⁷,Yu Byung‐Yong⁸,Yu Kyung‐Sang⁴,Lee Howard⁴⁹

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics CHA Bundang Medical Center CHA University Seongnam Korea

2. BioCore Co., Ltd. Seoul Korea

3. Korean Institute of Radiological and Medical Science Seoul Korea

4. Department of Clinical Pharmacology and Therapeutics Seoul National University College of Medicine and Hospital Seoul Korea

5. Department of Clinical Pharmacology and Therapeutics Chung Buk National University Hospital College of Medicine Cheongju‐si Chungcheongbuk‐do Korea

6. Clinical Trial Center Hanyang University Seoul Hospital Seoul Korea

7. Drug Metabolism and Bioanalysis Laboratory College of Pharmacy The Catholic University of Korea Bucheon Korea

8. Korea Institute of Science and Technology Seoul Korea

9. Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology Seoul National University Seoul Korea

Funder

Korea Health Industry Development Institute

National Research Foundation of Korea

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12848

Reference31 articles.

1. Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

2. What is the Objective of the Mass Balance Study? A Retrospective Analysis of Data in Animal and Human Excretion Studies Employing Radiolabeled Drugs

3. Species similarities and differences in pharmacokinetics;Lin J.H.;Drug Metab. Dispos.,1995

4. Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals

5. The Enzymes, Regulation, and Genetics of Bile Acid Synthesis

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