Immunological characteristics and T-cell receptor clonal diversity in children with systemic juvenile idiopathic arthritis undergoing T-cell-depleted autologous stem cell transplantation

Author:

Wu Qiong1,Pesenacker Anne M.1,Stansfield Alka2,King Douglas3,Barge Dawn4,Foster Helen E.5,Abinun Mario45,Wedderburn Lucy R.16

Affiliation:

1. Rheumatology Unit; UCL Institute of Child Health; University College London; London UK

2. Scientific Research Laboratory; Cell Medica; London UK

3. Division of Infection and Immunity; Department of Immunology; University College; London UK

4. Department of Paediatric Immunology; Great North Children's Hospital; Newcastle upon Tyne Hospitals NHS Foundation Trust; Newcastle upon Tyne UK

5. Musculoskeletal Research Group; Institute of Cellular Medicine; Newcastle University, and Great North Children's Hospital; London UK

6. Arthritis Research UK Centre for Adolescent Rheumatology; University College; London UK

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference29 articles.

1. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001;Petty;J Rheumatol,2004

2. Juvenile idiopathic arthritis;Ravelli;Lancet,2007

3. Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions;Mellins;Nat Rev Rheumatol,2011

4. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: functional outcome;Packham;Rheumatology (Oxford),2002

5. Autologous T cell depleted haematopoietic stem cell transplantation in children with severe juvenile idiopathic arthritis in the UK (2000-2007);Abinun;Mol Immunol,2009

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