Measuring factor IX activity of nonacog beta pegol with commercially available one-stage clotting and chromogenic assay kits: a two-center study
Author:
Affiliation:
1. Coagulation Department; Sheffield Teaching Hospitals; Sheffield UK
2. Department of Clinical Chemistry; Skåne University Hospital; Malmö Sweden
3. Novo Nordisk A/S; Novo Nordisk Park; Måløv Denmark
4. Novo Nordisk A/S; Søborg; Denmark
Funder
Physicians World Europe GmbH (Mannheim, Germany)
Novo Nordisk
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.13348/fullpdf
Reference26 articles.
1. Guidelines for the management of hemophilia;Srivastava;Haemophilia,2013
2. Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide;Ostergaard;Blood,2011
3. Comparative field study: impact of laboratory assay variability on the assessment of recombinant factor IX Fc fusion protein (rFIXFc) activity;Sommer;Thromb Haemost,2014
4. Generation and biochemical characterization of glycoPEGylated factor VIIa derivatives;Stennicke;Thromb Haemost,2008
5. Recombinant long-acting glycoPEGylated factor IX in hemophilia B: a multinational randomized phase 3 trial;Collins;Blood,2014
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1. Field Study and Correlative Studies of Factor IX Variant FIX-R338L in Participants Treated with Fidanacogene Elaparvovec;Thrombosis and Haemostasis;2024-06-11
2. High variability in Factor IX one‐stage assay in samples spiked with nonacog beta pegol among different pairs of reagent/detection system;International Journal of Laboratory Hematology;2023-09-13
3. Biodistribution of recombinant factor IX, extended half-life recombinant factor IX Fc fusion protein, and glycoPEGylated recombinant factor IX in hemophilia B mice;Blood Coagulation & Fibrinolysis;2023-07-17
4. Differences in wild-type– and R338L-tenase complex formation are at the root of R338L-factor IX assay discrepancies;Blood Advances;2023-02-06
5. Factor VIII and Factor IX Activity Measurements for Hemophilia Diagnosis and Related Treatments;Seminars in Thrombosis and Hemostasis;2022-12-06
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