The Age-dependence of atrial arrhythmogenicity in Scn5a+/−murine hearts reflects alterations in action potential propagation and recovery-Reference-Cited by-同舟云学术

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The Age-dependence of atrial arrhythmogenicity in Scn5a+/−murine hearts reflects alterations in action potential propagation and recovery

Published:2012-05-29 Issue:6 Volume:39 Page:518-527
ISSN:0305-1870
Container-title:Clinical and Experimental Pharmacology and Physiology
language:en
Short-container-title:Clin Exp Pharmacol Physiol

Author:

Guzadhur Laila¹,Jiang Wenhui²,Pearcey Sarah M¹,Jeevaratnam Kamalan,Duehmke Rudy M¹,Grace Andrew A³,Lei Ming⁴,Huang Christopher L-H

Affiliation:

1. Physiological Laboratory; University of Cambridge; Cambridge; UK

2. Medical College of Xi'an Jiaotong University; Xi'an; China

3. Department of Biochemistry; University of Cambridge; Cambridge; UK

4. Institute of Cardiovascular Sciences; University of Manchester; Manchester; UK

Publisher

Wiley

Subject

Physiology (medical),Pharmacology,Physiology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1440-1681.2012.05706.x/fullpdf

Reference46 articles.

1. Impact of atrial fibrillation on the risk of death: The Framingham Heart Study;Benjamin;Circulation,1998

2. Atrial fibrillation as an independent risk factor for stroke: The Framingham Study;Wolf;Stroke,1991

3. Aged atria: Electrical remodeling conducive to atrial fibrillation;Dun;J. Interv. Card. Electrophysiol.,2009

4. Identification of a genetic locus for familial atrial fibrillation;Brugada;N. Engl. J. Med.,1997

5. Persistent atrial fibrillation is associated with reduced risk of Torsades de Pointes in patients with drug-induced long QT syndrome;Darbar;J. Am. Coll. Cardiol.,2008

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1. Genetic background determines the severity of age-dependent cardiac structural abnormalities and arrhythmia susceptibility in Scn5a-1798insD mice;Europace;2024-06

2. Gene therapy targeting protein trafficking regulator MOG1 in mouse models of Brugada syndrome, arrhythmias, and mild cardiomyopathy;Science Translational Medicine;2022-06-08

3. Transcriptional profiles of genes related to electrophysiological function in Scn5a +/− murine hearts;Physiological Reports;2021-10

4. Cardiomyocyte ionic currents in intact young and aged murine Pgc-1β−/− atrial preparations;Mechanisms of Ageing and Development;2018-01

5. The impact of age and frailty on ventricular structure and function in C57BL/6J mice;The Journal of Physiology;2017-05-14

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