Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio

Author:

Gardiner Sharon J,Gearry Richard B,Burt Michael J,Chalmers-Watson Teresa,Chapman Bruce A,Ross Alison G,Stedman Catherine A M,Huelsen Alexander,Barclay Murray L

Publisher

Wiley

Subject

Gastroenterology,Hepatology

Reference30 articles.

1. Pancytopenia associated with the interaction of allopurinol and azathioprine;Garcia-Ortiz;J. Pharm. Technol.,1991

2. Allopurinol-azathioprine interaction;Boyd;J. Intern. Med.,1991

3. Azathioprine and allopurinol: the price of an avoidable drug interaction;Kennedy;Ann. Pharmacother.,1996

4. Allopurinol and azathioprine. Fatal interaction;Adverse Drug Reactions Advisory Committee;Med. J. Aust.,1980

5. Inhibition of first-pass metabolism in cancer chemotherapy: interaction of 6-mercaptopurine and allopurinol;Zimm;Clin. Pharmacol. Ther.,1983

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