1. Center for Regenerative Medicine and Skeletal Development, Department of Reconstructive Sciences, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, Connecticut 06030, USA;
2. Department of Biochemistry and Molecular Biology, Oregon Health Sciences University, Portland, Oregon; and
3. Departments of Obstetrics, Gynecology, and Reproductive Sciences; and Pathology and Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA