Novel approaches to mitigating parathion toxicity: targeting cytochrome P450-mediated metabolism with menadione

Author:

Jan Yi-Hua1,Richardson Jason R.2,Baker Angela A.1,Mishin Vladimir3,Heck Diane E.4,Laskin Debra L.3,Laskin Jeffrey D.1

Affiliation:

1. Department of Environmental and Occupational Health; Rutgers University School of Public Health; Piscataway New Jersey

2. Department of Pharmaceutical Sciences; Northeast Ohio Medical University; Rootstown Ohio

3. Department of Pharmacology and Toxicology; Rutgers University Ernest Mario School of Pharmacy; Piscataway New Jersey

4. Department of Environmental Health Science; New York Medical College; Valhalla New York

Funder

National Institutes of Health

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference38 articles.

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3. Neurotoxic Pesticides

4. Treatment of acute organophosphate poisoning;Lotti;Med. J. Aust,1991

5. Structural requirements of acetylcholinesterase reactivators;Kuca;Mini Rev. Med. Chem,2006

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