Rubella virus‐associated necrotizing granulomatous inflammation with extensive eyelid, ocular, and orbital involvement

Author:

Pimentel Matthew A.1ORCID,Kim Donna H.2,Walker Lorne W.3,Noelck Michelle B.4,Perelygina Ludmila5,Kripps Kimberly A.6,Cartwright Victoria W.7,Funk Tracy1,Green Sarah8,Kuo Annie2,Ng John2,Ophaug Solveig L.1,Passo Ross2,Redd Travis2,Small Alison1

Affiliation:

1. Department of Dermatology Oregon Health and Science University Portland Oregon USA

2. Department of Ophthalmology Oregon Health and Science University Portland Oregon USA

3. Division of Pediatric Infectious Diseases Oregon Health and Sciences University Portland Oregon USA

4. Department of Pediatrics Oregon Health and Science University Portland Oregon USA

5. Division of Viral Diseases Centers for Disease Control and Prevention Atlanta Georgia USA

6. Department of Molecular and Medical Genetics Oregon Health & Science University Portland Oregon USA

7. Department of Pediatrics, Division of Rheumatology Randall Children's Hospital at Legacy Emanuel Portland Oregon USA

8. Department of Pediatrics, Pediatric Hospital Medicine Oregon Health and Science University Portland Oregon USA

Abstract

AbstractWe present a case of cutaneous granulomatous disease associated with rubella virus in a 4‐year‐old girl without an identifiable immunodeficiency. In this case, a combination of anti‐inflammatory, anti‐viral, and anti‐neutrophil therapies successfully treated vision‐threatening eyelid, conjunctival, scleral, and orbital inflammation.

Publisher

Wiley

Subject

Dermatology,Pediatrics, Perinatology and Child Health

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