1. Royal United Hospital; NHS Trust; Bath UK
2. NIAA Health Services Research Centre; Royal College of Anaesthetists; London UK
3. Integrative Physiology and Critical Illness Group; Clinical and Experimental Sciences; Faculty of Medicine; University of Southampton; Southampton UK
4. Anaesthesia and Critical Care Research Unit; University Hospital Southampton; NHS Foundation Trust; Southampton UK
5. NIHR Southampton Respiratory Biomedical Research Unit; Southampton UK