Secreted frizzled-related protein 5 (Sfrp5) decreases hepatic stellate cell activation and liver fibrosis

Author:

Chatani Norihiro1,Kamada Yoshihiro12,Kizu Takashi1,Ogura Satoshi1,Furuta Kunimaro1,Egawa Mayumi1,Hamano Mina1,Ezaki Hisao1,Kiso Shinichi1,Shimono Akihiko3,Ouchi Noriyuki4,Yoshida Yuichi1,Takehara Tetsuo1

Affiliation:

1. Department of Gastroenterology and Hepatology; Osaka University; Graduate School of Medicine; Suita Osaka Japan

2. Department of Molecular Biochemistry & Clinical Investigation; Osaka University Graduate School of Medicine; Suita Osaka Japan

3. TransGenic Inc; Kobe Hyogo Japan

4. Department of Molecular Cardiology; Nagoya University Graduate School of Medicine; Nagoya Aichi Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology of Japan

Publisher

Wiley

Subject

Hepatology

Reference37 articles.

1. The natural history of nonalcoholic fatty liver disease: a population-based cohort study;Adams;Gastroenterology,2005

2. Alcohollike liver disease in nonalcoholics a clinical and histologic comparison with alcohol-induced liver injury;Diehl;Gastroenterology,1988

3. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected];Hui;Gastroenterology,2003

4. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance;Hotamisligil;J Clin Invest,1995

5. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid;Fried;J Clin Endocrinol Metab,1998

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