Escherichia coliheme oxygenase modulates host innate immune responses

Author:

Maharshak Nitsan123,Ryu Hyungjin Sally1,Fan Ting-Jia1,Onyiah Joseph C.14,Schulz Stephanie5,Otterbein Sherrie L.6,Wong Ron5,Hansen Jonathan J.12,Otterbein Leo E.5,Carroll Ian M.1,Plevy Scott E.12

Affiliation:

1. Department of Medicine and Center for GI Biology and Diseases; University of North Carolina at Chapel Hill; Chapel Hill North Carolina 27599

2. Department of Microbiology and Immunology; University of North Carolina at Chapel Hill; Chapel Hill North Carolina 27599

3. Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center; Affiliated to the Sackler Faculty of Medicine, Tel Aviv University; Tel Aviv 6997801 Israel

4. Division of Gastroenterology and Hepatology; Department of Medicine; University of Colorado, Aurora, CO and Denver VA Medical Center; Denver Colorado 80220

5. Department of Pediatrics; Division of Neonatal and Developmental Medicine; Stanford University School of Medicine; Palo Alto California 94305

6. Department of Surgery, Beth Israel Deaconess Medical Center; Harvard Medical School; Boston Massachusetts 02115 USA

Funder

Crohn's and Colitis Foundation of America

National Institutes of Health

University of North Carolina at Chapel Hill

Publisher

Wiley

Subject

Virology,Immunology,Microbiology

Reference45 articles.

1. Cigarette smoking and ulcerative colitis;Jick;N Engl J Med,1983

2. Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine;Moore;Gastroenterology,2003

3. Cytoprotective and anti-inflammatory actions of carbon monoxide in organ injury and sepsis models;Ryter;Novartis Fdn Symp,2007

4. Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants;Sato;J Immunol,2001

5. Heme oxygenase-1: unleashing the protective properties of heme;Otterbein;Trends Immunol,2003

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