Identification of small molecule inhibitors of p27Kip1ubiquitination by high-throughput screening
Author:
Affiliation:
1. Antibiotics Laboratory; RIKEN; Hirosawa Wako-shi Saitama Japan
2. School of Biological Sciences; Universiti Sains Malaysia; Penang Malaysia
3. Global Research Cluster; RIKEN; Hirosawa Wako-shi Saitama Japan
Publisher
Wiley
Subject
Cancer Research,Oncology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/cas.12246/fullpdf
Reference50 articles.
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2. CDK inhibitors: positive and negative regulators of G1-phase progression;Sherr;Genes Dev,1999
3. The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy;Chu;Nat Rev Cancer,2008
4. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell-cycle arrest;Polyak;Genes Dev,1994
5. A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells;Slingerland;Mol Cell Biol,1994
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