A novel, palatable paediatric oral formulation of midazolam: pharmacokinetics, tolerability, efficacy and safety

Author:

Salman S.1,Tang E. K. Y.2,Cheung L. C.345,Nguyen M. N.2,Sommerfield D.6,Slevin L.3,Lim L. Y.2,von Ungern Sternberg B. S.61

Affiliation:

1. Faculty of Health and Medical Sciences; Medical School; University of Western Australia; Perth Australia

2. Division of Pharmacy; Faculty of Health and Medical Sciences; School of Allied Health; University of Western Australia; Perth Australia

3. Telethon Kids Institute; University of Western Australia; Perth Australia

4. School of Pharmacy and Biomedical Sciences; Curtin University; Perth Australia

5. Department of Pharmacy; Princess Margaret Hospital for Children; Perth Australia

6. Department of Anaesthesia and Pain Management; Princess Margaret Hospital for Children; Perth Australia

Funder

Australian and New Zealand Clinical Trials Registry

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

Reference13 articles.

1. A report from the pediatric formulations task force: perspectives on the state of child-friendly oral dosage forms;Zajicek;American Association of Pharmaceutical Scientists Journal,2013

2. 1902 ⁄ 2006 of the European Parliament and of the Council of 20 December 2006 amending Regulation 1901 ⁄ 2006 on medicinal products for paediatric use;European Parliament and the Council of the European Union Regulation (EC) n;Official Journal of the European Union,1902

3. Effect of drinks that are added as flavoring in oral midazolam premedication on sedation success;Isik;Pediatric Anesthesia,2008

4. Midazolam premedication in children: a comparison of two oral dosage formulations on sedation score and plasma midazolam levels;Brosius;Anesthesia and Analgesia,2003

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