Tannic acid inhibits EGFR/STAT1/3 and enhances p38/STAT1 signalling axis in breast cancer cells

Author:

Darvin Pramod1,Joung Youn Hee1,Kang Dong Young1,Sp Nipin1,Byun Hyo Joo1,Hwang Tae Sook1,Sasidharakurup Hema2,Lee Chi Ho3,Cho Kwang Hyun4,Park Kyung Do5,Lee Hak Kyo5,Yang Young Mok1

Affiliation:

1. Department of Pathology; School of Medicine; Institute of Biomedical Science and Technology; Konkuk University; Seoul South Korea

2. Amrita School of Biotechnology; Amrita Vishwa Vidyapeetham (Amrita University); Kollam India

3. Department of Food Science and Biotechnology of Animal Resources; Konkuk University; Seoul South Korea

4. National Institute of Animal Science, RDA; Cheonan South Korea

5. Department of Animal Biotechnology; Chonbuk National University; Jeonju South Korea

Funder

Konkuk University

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference57 articles.

1. CancerStats;Cancer Research UK,2013

2. Hwanggeumchal sorghum induces cell cycle arrest, and suppresses tumor growth and metastasis through jak2/stat pathways in breast cancer xenografts;Park;PLoS ONE,2012

3. Sorghum polyphenol suppresses the growth as well as metastasis of colon cancer xenografts through co-targeting jak2/stat3 and pi3k/akt/mtor pathways;Darvin;J Funct Foods,2015

4. Tannic acid is an inhibitor of CXCL12 (SDF-1α)/CXCR4 with antiangiogenic activity;Chen;Clin Cancer Res,2003

5. Tannic acid raises survival rate of mice bearing syngeneic tumors;Koide;Cancer Biother Radiopharm,1999

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