TheCDKN2A/p16INK4a5′UTR sequence and translational regulation: impact of novel variants predisposing to melanoma-Reference-Cited by-同舟云学术

TheCDKN2A/p16INK4a5′UTR sequence and translational regulation: impact of novel variants predisposing to melanoma

Published:2015-12-17 Issue:2 Volume:29 Page:210-221
ISSN:1755-1471
Container-title:Pigment Cell & Melanoma Research
language:en
Short-container-title:Pigment Cell Melanoma Res.

Author:

Andreotti Virginia¹²,Bisio Alessandra³,Bressac-de Paillerets Brigitte⁴,Harland Mark⁵,Cabaret Odile⁴,Newton-Bishop Julia⁵,Pastorino Lorenza¹²,Bruno William¹²,Bertorelli Roberto⁶,De Sanctis Veronica⁶,Provenzani Alessandro⁷,Menin Chiara⁸,Fronza Gilberto⁹,Queirolo Paola¹⁰,Spitale Robert C.¹¹,Bianchi-Scarrà Giovanna¹²,Inga Alberto³,Ghiorzo Paola¹²

Affiliation:

1. Department of Internal Medicine and Medical Specialties; DiMI; University of Genoa; Genoa Italy

2. Genetics of Rare Cancers; IRCCS AOU San Martino-IST; Genoa Italy

3. Laboratory of Transcriptional Networks; Centre for Integrative Biology; CIBIO; University of Trento; Trento Italy

4. Department of Biopathology and INSERM U1186; Gustave Roussy; Villejuif France

5. Section of Epidemiology and Biostatistics; Leeds Institute of Cancer and Pathology; University of Leeds; Leeds UK

6. NGS Core Facility; Centre for Integrative Biology; CIBIO; University of Trento; Trento Italy

7. Laboratory of Genomic Screening; Centre for Integrative Biology; CIBIO; University of Trento; Trento Italy

8. Immunology and Molecular Oncology Unit; Veneto Institute of Oncology IOV-IRCCS; Padua Italy

9. Mutagenesis Unit; IRCCS AOU San Martino -IST; Genoa Italy

10. Medical Oncology Unit; IRCCS AOU San Martino-IST; Genoa Italy

11. Department of Pharmaceutical Sciences; University of California; Irvine CA USA

Funder

Università degli Studi di Genova

IRCCS AOU San Martino-IST 5 per mille per la Ricerca Corrente

Associazione Italiana per la Ricerca sul Cancro

Institut National Du Cancer

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/pcmr.12444/fullpdf

Reference40 articles.

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2. Genetics of familial melanoma: 20 years after CDKN2A;Aoude;Pigment Cell Melanoma Res.,2015

3. Functional analysis of CDKN2A/p16INK4a 5′-UTR variants predisposing to melanoma;Bisio;Hum. Mol. Genet.,2010

4. The 5′-untranslated region of p16INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding;Bisio;Oncotarget,2015

5. Clinical genetic testing for familial melanoma in Italy: a cooperative study;Bruno;J. Am. Acad. Dermatol.,2009

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