Affiliation:
1. EverKeen Medical Centre Hong Kong Hong Kong
2. Perfect Skin Solution Hong Kong Hong Kong
3. London Heart Practice Hong Kong Hong Kong
4. Asia‐Pacific Aesthetic Academy Hong Kong Hong Kong
5. Shanthalamd Laser & Aesthetic Center Peabody Massachusetts USA
6. Medaes Medical Limited Hong Kong Hong Kong
7. Piena Aesthetic Clinic Gangnam Seoul South Korea
8. Division in Anatomy and Developmental Biology Department of Oral Biology Human Identification Research Institute BK21 FOUR Project Yonsei University College of Dentistry Seoul South Korea
9. Maylin Clinic (Apgujeong) Seoul South Korea
Abstract
AbstractBackgroundPhotoaging is a process of the architecture of normal skin damaged by ultraviolet radiation. Topical cosmeceuticals have been used to treat this condition. The authors aimed to understand the mechanism and level of evidence of different commonly used cosmeceuticals used to treat photodamaged skin.ObjectiveA range of commonly used topical cosmeceuticals (botanicals, peptides, and hydroquinone) has been used in cosmetic medicine for many years to treat photodamaged skin. This review article compares their efficacy and level of evidence.Material and methodsThis study was a systematic review to evaluate the efficacy of different topical cosmeceuticals. Keywords including “Photoaging,” “Azelaic acid,” “Soy,” “Green Tea,” “Chamomile,” “Ginkgo,” “Tea Tree Oil,” “Resveratrol,” “Cucumber,” “Ginseng,” “Centella asiatica,” “Licorice Root,” “Aloe Vera,” “Peptides,” “Argireline,” “Hydroquinone,” were typed on OVID, PUBMED, MEDLINE for relevant studies published on photoaging treatment.ResultsMost of the evidence behind cosmeceuticals is of high‐quality ranging from Level I to Level II. In particular, the evidence base behind peptides is the strongest with most studies achieving Level Ib status in the evidence hierarchy.ConclusionTopical cosmeceuticals like botanicals, peptides and hydroquinone can effectively treat photodamaged skin
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