The highly selective mGlu 2 receptor positive allosteric modulator LY‐487,379 alleviates l ‐DOPA‐induced dyskinesia in the 6‐OHDA‐lesioned rat model of Parkinson's disease-Reference-Cited by-同舟云学术

The highly selective mGlu 2 receptor positive allosteric modulator LY‐487,379 alleviates l ‐DOPA‐induced dyskinesia in the 6‐OHDA‐lesioned rat model of Parkinson's disease

Published:2020-02-12 Issue:12 Volume:51 Page:2412-2422
ISSN:0953-816X
Container-title:European Journal of Neuroscience
language:en
Short-container-title:Eur J Neurosci

Author:

Hamadjida Adjia¹^ORCID,Sid‐Otmane Lamia²,Kwan Cynthia¹,Frouni Imane¹²,Nafade Vaidehi¹,Bédard Dominique¹,Gagnon Dave³,Wallman Marie‐Josée³,Rouillard Claude⁴,Parent André³,Parent Martin³,Huot Philippe¹²⁵⁶

Affiliation:

1. Neurodegenerative Disease Group Montreal Neurological Institute Montreal QC Canada

2. Département de Pharmacologie et Physiologie Université de Montréal Montreal QC Canada

3. Centre de Recherche CERVO Quebec City QC Canada

4. Centre de Recherche du Centre Hospitalier Universitaire de Québec Quebec City QC Canada

5. Department of Neurology and Neurosurgery McGill University Montreal QC Canada

6. Movement Disorder Clinic Division of Neurology Department of Neuroscience McGill University Health Centre Montreal QC Canada

Funder

Fonds de Recherche du Québec - Santé

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada

Michael J. Fox Foundation for Parkinson's Research

Parkinson Canada

Weston Brain Institute

Publisher

Wiley

Subject

General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/ejn.14679

Reference43 articles.

1. Frequency of levodopa‐related dyskinesias and motor fluctuations as estimated from the cumulative literature

2. The Origin and Neuronal Function ofIn VivoNonsynaptic Glutamate

3. Amantadine Inhibits NMDA Receptors by Accelerating Channel Closure during Channel Block

4. Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum

5. Ratings of L ‐DOPA‐Induced Dyskinesia in the Unilateral 6‐OHDA Lesion Model of Parkinson's Disease in Rats and Mice

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