Oncogenic properties via <scp>MAPK</scp> signaling of the <scp>SOX5‐RAF1</scp> fusion gene identified in a <i>wild‐type</i> <scp>NRAS</scp> / <scp>BRAF</scp> giant congenital nevus-Reference-Cited by-同舟云学术

Oncogenic properties via MAPK signaling of the SOX5‐RAF1 fusion gene identified in a wild‐type NRAS / BRAF giant congenital nevus

Published:2022-05-31 Issue:4 Volume:35 Page:450-460
ISSN:1755-1471
Container-title:Pigment Cell & Melanoma Research
language:en
Short-container-title:Pigment Cell Melanoma Res

Author:

Vinyals Antònia¹,Ferreres Josep R.¹²,Calbet‐Llopart Neus³,Ramos Raquel¹,Tell‐Martí Gemma³⁴,Carrera Cristina³⁴,Marcoval Joaquim²,Puig Susana³⁴,Malvehy Josep³⁴,Puig‐Butillé Joan Anton⁴⁵,Fabra Àngels¹

Affiliation:

1. Oncobell Program Bellvitge Biomedical Research Institute (IDIBELL) Barcelona Spain

2. Dermatology Service IDIBELL – Hospital Universitari de Bellvitge Barcelona Spain

3. Dermatology Department IDIBAPS Hospital Clínic de Barcelona University of Barcelona Barcelona Spain

4. Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER) Instituto de Salud Carlos III Barcelona Spain

5. Molecular Biology CORE Laboratory Melanoma Unit IDIBAPS Hospital Clínic de Barcelona University of Barcelona Barcelona Spain

Publisher

Wiley

Subject

Dermatology,General Biochemistry, Genetics and Molecular Biology,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/pcmr.13044

Reference40 articles.

1. CRAF R391W is a melanoma driver oncogene

2. Malignant melanoma with areas of rhabdomyosarcomatous differentiation arising in a giant congenital nevus with RAF1 gene fusion

3. Congenital Melanocytic Nevi Frequently Harbor NRAS Mutations but no BRAF Mutations

4. The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene

5. Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses

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