Ribosomal protein S6 is hyperactivated and differentially phosphorylated in epidermal lesions of patients with psoriasis and atopic dermatitis

Author:

Ruf M.T.12,Andreoli A.12,Itin P.3,Pluschke G.12,Schmid P.12

Affiliation:

1. Swiss Tropical and Public Health Institute; Socinstrasse 57 4002 Basel Switzerland

2. University of Basel; Basel Switzerland

3. Department of Dermatology; University Hospital; Basel Switzerland

Funder

UBS Optimus Foundation

Publisher

Wiley

Subject

Dermatology

Reference15 articles.

1. Physiological roles of ribosomal protein S6: one of its kind;Meyuhas;Int Rev Cell Mol Biol,2008

2. Mitogen-activated 70K S6 kinase. Identification of in vitro 40 S ribosomal S6 phosphorylation sites;Ferrari;J Biol Chem,1991

3. Ordered multisite phosphorylation of Xenopus ribosomal protein S6 by S6 kinase II;Wettenhall;J Biol Chem,1992

4. Rapamycin-FKBP specifically blocks growth-dependent activation of and signalling by the 70 kd S6 protein kinases;Chung;Cell,1992

5. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation;Roux;J Biol Chem,2007

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