CRISPR /Cas9‐mediated gene knockout for DNA methyltransferase Dnmt3a in CHO cells displays enhanced transgenic expression and long‐term stability-Reference-Cited by-同舟云学术

CRISPR /Cas9‐mediated gene knockout for DNA methyltransferase Dnmt3a in CHO cells displays enhanced transgenic expression and long‐term stability

Published:2018-05-30 Issue:9 Volume:22 Page:4106-4116
ISSN:1582-1838
Container-title:Journal of Cellular and Molecular Medicine
language:en
Short-container-title:J. Cell. Mol. Med.

Author:

Jia Yan‐Long¹²,Guo Xiao¹²,Lu Jiang‐Tao¹²,Wang Xiao‐Yin²³,Qiu Le‐Le³,Wang Tian‐Yun²³^ORCID

Affiliation:

1. College of Pharmacy Xinxiang Medical University Xinxiang Henan China

2. International Joint Research Laboratory for Recombiant Pharmaceutical Protein Expression System of Henan Xinxiang Medical University Xinxiang Henan China

3. School of Basic Medicine Xinxiang Medical University Xinxiang Henan China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.13687

Reference43 articles.

1. Cellular engineering for therapeutic protein production: product quality, host modification, and process improvement

2. New Mammalian Expression Systems

3. Gene silencing as a threat to the success of gene therapy

4. A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?

5. A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular biomarkers identification and applications in CHO bioprocessing;Journal of Biotechnology;2024-09

2. Overexpression of YTHDF3 increases the specific productivity of the recombinant protein in CHO cells by promoting the translation process;Biotechnology Journal;2024-04

3. Omics and CRISPR in CHO bioproduction: a state-of-the-art review;Biotechnology and Bioprocess Engineering;2024-03-29

4. Recombinant therapeutic proteins degradation and overcoming strategies in CHO cells;Applied Microbiology and Biotechnology;2024-01-29

5. CRISPR Technologies in Chinese Hamster Ovary Cell Line Engineering;International Journal of Molecular Sciences;2023-05-02