The mechanism of Psoralen and Isopsoralen hepatotoxicity as revealed by hepatic gene expression profiling in SD rats-Reference-Cited by-同舟云学术

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The mechanism of Psoralen and Isopsoralen hepatotoxicity as revealed by hepatic gene expression profiling in SD rats

Published:2019-08-08 Issue:6 Volume:125 Page:527-535
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

Song Lei¹²,Yu Bin¹,Yang Li²,Wang Zhao‐xin²,Zhang Yue²³,Yu Ying‐li²⁴,Zhou Kun²³⁴

Affiliation:

1. School of Integrative Medicine Tianjin University of Traditional Chinese Medicine Tianjin China

2. Institute of Traditional Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China

3. Key Laboratory of Formula of Traditional Chinese Medicine, Ministry of Education Tianjin University of Traditional Chinese Medicine Tianjin China

4. Tianjin State Key Laboratory of Modern Chinese Medicine Tianjin China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.13287

Reference29 articles.

1. Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi)

2. Psoralea corylifolia Linn.-"Kushtanashini"

3. Studies on the metabolites difference of psoralen/isopsoralen in human and six mammalian liver microsomes in vitro by UHPLC–MS/MS

4. A Case of Acute Cholestatic Hepatitis Associated with the Seeds ofPsoralea corylifolia(Boh-Gol-Zhee)

5. Liver injury associated with the use ofFructus Psoraleae(Bol-gol-zhee or Bu-gu-zhi) and its related proprietary medicine

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1. Anti-tumor effect and hepatotoxicity mechanisms of psoralen;Frontiers in Pharmacology;2024-08-05

2. Mechanistic study of cytochrome P450 enzyme-mediated cytotoxicity of psoralen and isopsoralen;Food and Chemical Toxicology;2023-10

3. Discovery of bakuchiol as an AIM2 inflammasome activator and cause of hepatotoxicity;Journal of Ethnopharmacology;2022-11

4. Psoralen and isopsoralen from Psoraleae Fructus aroused hepatotoxicity via induction of aryl hydrocarbon receptor-mediated CYP1A2 expression;Journal of Ethnopharmacology;2022-10

5. Transcriptomics and metabolomics reveal the role of CYP1A2 in psoralen/isopsoralen‐induced metabolic activation and hepatotoxicity;Phytotherapy Research;2022-09-03

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