Using a prime and pull approach, lentivector vaccines expressing Ag85A induce immunogenicity but fail to induce protection againstMycobacterium bovisbacillus Calmette-Guérin challenge in mice
Author:
Affiliation:
1. Division of Infection and Immunity; University College London; London UK
2. Division of Medicine; University College London; London UK
3. National Institute of Biological Standards and Control; South Mimms Herts UK
Funder
UCL/UCLH BRC
MRC Clinical Research Fellowship
Department of Health's NIHR Biomedical Research Centre's
NIHR Academic Clinical Lectureship
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/imm.12498/fullpdf
Reference20 articles.
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3. The success and failure of BCG - implications for a novel tuberculosis vaccine;Andersen;Nat Rev Microbiol,2005
4. A vaccine strategy that protects against genital herpes by establishing local memory T cells;Shin;Nature,2012
5. Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial;Tameris;Lancet,2013
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