Clonal Replacement Underlies Spontaneous Remission in Paroxysmal Nocturnal Haemoglobinuria

Author:

Babushok Daria V.12,Stanley Natasha2,Xie Hongbo M.3,Huang Hugh2,Bagg Adam4,Olson Timothy S.25,Bessler Monica12

Affiliation:

1. Division of Hematology; Department of Medicine; Hospital of the University of Pennsylvania; Philadelphia PA USA

2. Comprehensive Bone Marrow Failure Center; Division of Hematology; Department of Pediatrics; Children's Hospital of Philadelphia; Philadelphia PA USA

3. Center for Biomedical Informatics; Children's Hospital of Philadelphia; Philadelphia PA USA

4. Department of Pathology and Laboratory Medicine; Hospital of the University of Pennsylvania; Philadelphia PA USA

5. Blood and Marrow Transplant Program; Division of Oncology; Department of Pediatrics; Children's Hospital of Philadelphia and University of Pennsylvania; Philadelphia PA USA

Funder

NHLBI/NIH

Aplastic Anemia and MDS International Foundation

American Society of Hematology

NCI/NIH

Buck Family Endowed Chair in Hematology

NIH/NIDDK

Publisher

Wiley

Subject

Hematology

Reference9 articles.

1. Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia;Babushok;Cancer Genetics,2015

2. Prolonged survival in paroxysmal nocturnal haemoglobinuria;Charache;Blood,1969

3. Acute leukaemia in paroxysmal nocturnal haemoglobinuria. Case report and review of the literature;Cornelis;Hematology and Cell Therapy,1996

4. Paroxysmal nocturnal haemoglobinuria: clinical manifestations, haematology, and nature of the disease;Dacie;Series Haematologica,1972

5. Neutral evolution in paroxysmal nocturnal haemoglobinuria;Dingli;Proceedings of the National Academy of Sciences of the United States of America,2008

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