Affiliation:
1. Moscow Clinical Hospital by Speransky Moscow Russia
2. Laboratory Angiopharm Private Clinic Moscow Russia
3. InMode Inc. Yokneam Israel
4. Division of Plastic Surgery, Department of Surgery Cedars Sinai Hospital Los Angeles California USA
5. Private Practice, Ghavami Plastic Surgery Beverly Hills California USA
6. Private Practice, SpaMedica Plastic Surgery Center Toronto Ontario Canada
Abstract
AbstractBackgroundThe negative effects of skin aging are primarily related to the destruction of dermal architectural structure. More specifically, this includes changes in the spatial arrangement of collagen, elastin fibers, mucopolysaccharides, proteoglycans, and ground substances.AimsThe purpose of this study is to investigate the histologic effects of dermal and subdermal tissue after a controlled single treatment with radiofrequency (RF) macroneedling. This therapy provides a controlled, localized, thermal effect on the dermis whereby triggering the body's own healing processes of extracellular matrix remodeling. Clinically benefits include skin tightening.MethodsBiopsies were obtained for histologic evaluation from four patients (n = 4), 4 weeks after completing a single RF macroneedling facial treatment.ResultsAge‐related changes of the dermal and subdermal architecture were observed at baseline. After treatment, all biopsies demonstrated an increase in epidermal cells, collagen, elastin, fibroblasts, vasculature, and a decrease in inflammatory cells.ConclusionsThe results of this histologic study confirm a significant “subsurfacing” thermal effect from the noncoagulative ascendant thermal injury. The obtained results characterize RF macroneedling therapy as an effective method for correcting age‐related changes in facial skin.