Affiliation:
1. Division of Pediatric Critical Care Medicine Washington University in St. Louis St Louis Missouri USA
2. Division of Pediatric Pulmonary Medicine Washington University in St. Louis St Louis Missouri USA
3. Therapy Services St. Louis Children's Hospital St Louis Missouri USA
4. Department of Cardiothoracic Surgery Washington University in St. Louis St Louis Missouri USA
Abstract
AbstractBackgroundExtracorporeal Membrane Oxygenation (ECMO) may be used as a bridge to lung transplantation in selected patients with end‐stage respiratory failure. Historically, ECMO use in this setting has been associated with poor outcomes Puri V et.al, J Thorac Cardiovasc Surg, 140:427. More recently, technical advances and the implementation of rehabilitation and ambulation while awaiting transplantation on ECMO have led to improved surgical and post‐transplant outcomes Kirkby S et.al, J Thorac Dis, 6:1024.MethodsWe illustrate the case of a 6‐year‐old child who received prolonged ECMO support as a bridge to lung re‐transplantation secondary to Chronic Lung Allograft Dysfunction (CLAD).ResultsEarly rehabilitation was key in improving the overall pre‐transplant conditioning during ECMO.ConclusionsDespite challenges associated with awake/ambulatory ECMO, the use of this strategy as a bridge to lung transplantation is feasible and has resulted in improved pre‐transplant conditioning and post‐transplant outcomes.
Subject
Transplantation,Pediatrics, Perinatology and Child Health