Survey of pediatric transplant center practices regarding COVID‐19 vaccine mandates for transplant candidates and living donors and use of COVID‐19‐positive deceased organs

Author:

Feldman Amy G.1ORCID,Beaty Brenda2,Everitt Melanie3ORCID,Goebel Jens4ORCID,Kempe Allison5ORCID,Pratscher Lauren6,Danziger‐Isakov Lara A.7ORCID

Affiliation:

1. Section of Pediatric Gastroenterology, Hepatology and Nutrition, Pediatric Liver Transplant Center, Digestive Health Institute University of Colorado School of Medicine and Children's Hospital Colorado Aurora Colorado USA

2. Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) University of Colorado School of Medicine and Children's Hospital Colorado Aurora Colorado USA

3. Pediatric Heart Transplant Program, Section of Pediatric Cardiology University of Colorado School of Medicine and Children's Hospital Colorado Aurora Colorado USA

4. Pediatrics and Human Development Section of Pediatric Nephrology, Helen DeVos Children's Hospital, Michigan State University Grand Rapids Michigan USA

5. Department of Pediatrics, Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) University of Colorado School of Medicine and Children's Hospital Colorado Aurora Colorado USA

6. Children's Hospital Colorado Aurora Colorado USA

7. Immunocompromised Host Infectious Disease, Cincinnati Children's Hospital Medical Center University of Cincinnati Cincinnati Ohio USA

Abstract

AbstractBackgroundCOVID‐19 vaccine is recommended for individuals ages ≥6 months; however, whether vaccination should be mandated for transplant candidates and living donors remains controversial. This study assessed COVID‐19 policies at US pediatric solid organ transplant centers.MethodsA 79‐item survey was emailed between March and April 2022 to 200 UNOS Medical Directors detailing center COVID‐19 vaccine policies for transplant candidates and living donors and use of grafts from COVID‐19‐positive deceased donors.ResultsThe response rate was 77% (154/200). For children aged 5–15 years, 23% (35/154 centers) have a COVID‐19 vaccine mandate, 27% (42/154) anticipate implementing a future mandate, and 47% (72/154) have not considered or do not anticipate implementing a mandate. For children ≥16 years, 32% (50/154 centers) have a COVID‐19 vaccine mandate, 25% (39/154) anticipate implementing a future mandate, and 40% (62/154) have not considered or do not anticipate implementing a mandate. The top two reasons for not implementing a COVID‐19 vaccine mandate were concerns about penalizing a child for their parent's decision and worsening inequities in transplant. Of 85 kidney and liver living donor centers, 32% (27/85) require vaccination of donors. Twenty percent (31/154) of centers accept organs from COVID‐19‐positive deceased donors.ConclusionsThere is great variation among pediatric SOT centers in both the implementation and details of COVID‐19 vaccine mandates for candidates and living donors. To guide more uniform policies, further data are needed on COVID‐19 disease, vaccine efficacy, and use of grafts from donors positive for COVID‐19 in the pediatric transplant population.

Funder

Agency for Healthcare Research and Quality

Publisher

Wiley

Subject

Transplantation,Pediatrics, Perinatology and Child Health

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