Pharmacokinetics of testosterone therapies in relation to diurnal variation of serum testosterone levels as men age

Author:

Pastuszak Alexander W.1ORCID,Gittelman Marc2,Tursi James P.3,Jaffe Jonathan S.3,Schofield David3,Miner Martin M.4

Affiliation:

1. University of Utah School of Medicine Salt Lake City Utah USA

2. 21st Century Oncology Uro‐Medix/GenesisCare Aventura Florida USA

3. Antares Pharma, Inc. Ewing New Jersey USA

4. Men's Health Center Miriam Hospital Providence Rhode Island USA

Publisher

Wiley

Subject

Urology,Endocrinology,Reproductive Medicine,Endocrinology, Diabetes and Metabolism

Reference99 articles.

1. US Food and Drug Administration.FDA Drug safety communication: FDA cautions about using testosterone products for low testosterone due to aging; requires labeling change to inform of possible increased risk of heart attack and stroke with use.2018. Accessed February 9 2020.https://www.fda.gov/drugs/drug‐safety‐and‐availability/fda‐drug‐safety‐communication‐fda‐cautions‐about‐using‐testosterone‐products‐low‐testosterone‐due.

2. Testosterone Therapy in Men With Hypogonadism: An Endocrine Society* Clinical Practice Guideline

3. Evaluation and Management of Testosterone Deficiency: AUA Guideline

4. Critical evaluation of different available guidelines for late‐onset hypogonadism

5. Loss of Circadian Rhythmicity in Blood Testosterone Levels with Aging in Normal Men*

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