An alternative intermittent eltrombopag dosing protocol for the treatment of chronic immune thrombocytopenia
Author:
Affiliation:
1. Center for HematologyMassachusetts General Hospital Cancer Center, Harvard Medical School Boston MA USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.13717
Reference12 articles.
1. GlaxoSmithKline.Promacta (eltrombopag) [prescribing information]. Research Triangle Park NC.2017.
2. Population PK/PD Modeling of Eltrombopag in Healthy Volunteers and Patients With Immune Thrombocytopenic Purpura and Optimization of Response-Guided Dosing
3. Phase 1 clinical study of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist
4. A Randomized, Open-Label, 5-Period, Balanced Crossover Study to Evaluate the Relative Bioavailability of Eltrombopag Powder for Oral Suspension (PfOS) and Tablet Formulations and the Effect of a High-Calcium Meal on Eltrombopag Pharmacokinetics When Administered With or 2 Hours Before or After PfOS
5. Effects of food and antacids on the pharmacokinetics of eltrombopag in healthy adult subjects: Two single-dose, open-label, randomized-sequence, crossover studies
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