Innovative personalized medicine in gastric cancer: time to move forward

Author:

Lee J.1,Kim K.-M.2,Kang W.K.1,Ou S.-H.I.3

Affiliation:

1. Department of Medicine; Division of Hematology-Oncology

2. Department of Pathology; Samsung Medical Center, Sungkyunkwan University School of Medicine; Seoul South Korea

3. Chao Family Comprehensive Cancer Center, Department of Internal Medicine, Division of Hematology-Oncology; University of California Irvine School of Medicine; Orange CA 92868-3298 USA

Publisher

Wiley

Subject

Genetics(clinical),Genetics

Reference58 articles.

1. Global cancer statistics;Jemal;CA Cancer J Clin,2011

2. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial;Bang;Lancet,2010

3. Ramucirumab monotherapy for previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (REGARD): an international, randomised, multicentre, placebo-controlled, phase 3 trial;Fuchs;Lancet,2014

4. RAINBOW: a global, phase III, randomized, double-blind study of ramucirumab plus paclitaxel versus placebo plus paclitaxel in the treatment of metastatic gastroesophageal junction (GEJ) and gastric adenocarcinoma following disease progression on first-line platinum- and fluoropyrimidine-containing combination therapy rainbow IMCL CP12-0922 (I4T-IE-JVBE);Hansjochen;J Clin Oncol,2014

5. Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): a better mousetrap? A review of the clinical evidence;Ou;Crit Rev Oncol Hematol,2012

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