Plasma chemistry reference intervals for adult multi‐drug‐resistance gene deficient Collies

Abstract

BackgroundDifferences in the reference intervals between dog breeds have been recognized for many years. Due to the importance of multi‐drug‐resistance 1‐deficient (MDR1) Collies in veterinary medicine, it is important to determine whether breed‐specific reference intervals are needed for this group.ObjectivesThe goal of this study was to establish plasma chemistry reference intervals for adult MDR1‐deficient Collies.MethodsPlasma samples collected from 110 healthy male and female adult MDR1‐deficient Collies were analyzed for 21 analytes on a Beckman AU480 clinical chemistry analyzer. Reference intervals were established using a nonparametric statistical method.ResultsReference intervals were established for 21 biochemical measurands in healthy adult MDR1‐deficient Collies.ConclusionPlasma chemistry reference intervals for MDR1‐deficient Collies were clinically similar to intervals earlier created for Beagles. Intervals for male and female MDR1‐deficient Collies were very similar to each other.