A birch sublingual allergy immunotherapy tablet reduces rhinoconjunctivitis symptoms when exposed to birch and oak and induces IgG4 to allergens from all trees in the birch homologous group
Author:
Affiliation:
1. Inflamax Research Limited; Mississauga Ontario Canada
2. ALK; Hoersholm Denmark
Funder
ALK, Hoersholm, Denmark
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/all.13606/fullpdf
Reference26 articles.
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2. The principle of homologous groups in regulatory affairs of allergen products - a proposal;Lorenz;Int Arch Allergy Immunol,2009
3. EMEA Guideline on the clinical development of products for specific immunotherapy for the treatment of allergic diseases
4. Recombinant birch pollen allergens (rBet v 1 and rBet v 2) contain most of the IgE epitopes present in birch, alder, hornbeam, hazel, and oak pollen: a quantitative IgE inhibition study with sera from different populations;Niederberger;J Allergy Clin Immunol,1998
5. Transition from a botanical to a molecular classification in tree pollen allergy: implications for diagnosis and therapy;Mothes;Int Arch Allergy Immunol,2004
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